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Arylformamidase

In enzymology, an arylformamidase (EC 3.5.1.9) is an enzyme that catalyzes the chemical reaction

arylformamidase
Identifiers
EC no.3.5.1.9
CAS no.156229-75-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
N-formyl-L-kynurenine + H2O formate + L-kynurenine

Thus, the two substrates of this enzyme are N-formyl-L-kynurenine and H2O, whereas its two products are formate and L-kynurenine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is aryl-formylamine amidohydrolase. Other names in common use include kynurenine formamidase, formylase, formylkynureninase, formylkynurenine formamidase, formamidase I, and formamidase II. This enzyme participates in tryptophan metabolism and glyoxylate and dicarboxylate metabolism.

References edit

  • HAYAISHI O, STANIER RY (1951). "The bacterial oxidation of tryptophan. III. Enzymatic activities of cell-free extracts from bacteria employing the aromatic pathway". J. Bacteriol. 62 (6): 691–709. PMC 386191. PMID 14907621.
  • JAKOBY WB (1954). "Kynurenine formamidase from Neurospora". J. Biol. Chem. 207 (2): 657–63. PMID 13163050.
  • MEHLER AH, KNOX WE (1950). "The conversion of tryptophan to kynurenine in liver. II. The enzymatic hydrolysis of formylkynurenine". J. Biol. Chem. 187 (1): 431–8. PMID 14794728.


arylformamidase, enzymology, arylformamidase, enzyme, that, catalyzes, chemical, reactionarylformamidaseidentifiersec, 9cas, 156229, 3databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic, pathwaypriamprofilepdb, str. In enzymology an arylformamidase EC 3 5 1 9 is an enzyme that catalyzes the chemical reactionarylformamidaseIdentifiersEC no 3 5 1 9CAS no 156229 75 3DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins N formyl L kynurenine H2O displaystyle rightleftharpoons formate L kynurenine Thus the two substrates of this enzyme are N formyl L kynurenine and H2O whereas its two products are formate and L kynurenine This enzyme belongs to the family of hydrolases those acting on carbon nitrogen bonds other than peptide bonds specifically in linear amides The systematic name of this enzyme class is aryl formylamine amidohydrolase Other names in common use include kynurenine formamidase formylase formylkynureninase formylkynurenine formamidase formamidase I and formamidase II This enzyme participates in tryptophan metabolism and glyoxylate and dicarboxylate metabolism References editHAYAISHI O STANIER RY 1951 The bacterial oxidation of tryptophan III Enzymatic activities of cell free extracts from bacteria employing the aromatic pathway J Bacteriol 62 6 691 709 PMC 386191 PMID 14907621 JAKOBY WB 1954 Kynurenine formamidase from Neurospora J Biol Chem 207 2 657 63 PMID 13163050 MEHLER AH KNOX WE 1950 The conversion of tryptophan to kynurenine in liver II The enzymatic hydrolysis of formylkynurenine J Biol Chem 187 1 431 8 PMID 14794728 Portal nbsp Biology This EC 3 5 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Arylformamidase amp oldid 1172340434, wikipedia, wiki, book, books, library,

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