It is significant only because it can be misdiagnosed as a cancer. It may be seen in a completely normal pregnancy.
Diagnosisedit
It is characterized by nuclear enlargement and may also have any of the following: an irregular nuclear membrane, granular chromatin, centronuclear vacuolization, and pseudonuclear inclusions.[1]
^ abcdArias-Stella, J. (Jan 2002). "The Arias-Stella reaction: facts and fancies four decades after". Adv Anat Pathol. 9 (1): 12–23. doi:10.1097/00125480-200201000-00003. PMID 11756756. S2CID 26249687.
^Arias-Stella, J. (Aug 1954). "Atypical endometrial changes associated with the presence of chorionic tissue". Arch Pathol. 58 (2): 112–28. PMID 13170908.
Bibliographyedit
Textbook of Obstetrics by D.C. Dutta Page no. 180. ISBN81-7381-142-3
January 01, 1970
arias, stella, reaction, also, arias, stella, phenomenon, benign, change, endometrium, associated, with, presence, chorionic, tissue, micrograph, showing, endometrium, progesterone, primarily, cytologically, looks, like, malignancy, historically, diagnosed, en. Arias Stella reaction also Arias Stella phenomenon is a benign change in the endometrium associated with the presence of chorionic tissue 1 Micrograph showing Arias Stella reaction in endometrium Arias Stella reaction is due to progesterone primarily Cytologically it looks like a malignancy and historically it was diagnosed as endometrial cancer 1 Contents 1 Significance 2 Diagnosis 3 History 4 See also 5 References 5 1 BibliographySignificance editIt is significant only because it can be misdiagnosed as a cancer It may be seen in a completely normal pregnancy Diagnosis editIt is characterized by nuclear enlargement and may also have any of the following an irregular nuclear membrane granular chromatin centronuclear vacuolization and pseudonuclear inclusions 1 Five subtypes are recognized 1 Minimal atypia Early secretory pattern Secretory or hypersecretory pattern Regenerative proliferative or nonsecretory pattern Monstrous cell pattern History editIt was first described by Javier Arias Stella a Peruvian pathologist in 1954 2 See also editChoriocarcinoma Chorioangioma Herpes Nuclear atypia Nuclear pleomorphism Molar ectopicReferences edit a b c d Arias Stella J Jan 2002 The Arias Stella reaction facts and fancies four decades after Adv Anat Pathol 9 1 12 23 doi 10 1097 00125480 200201000 00003 PMID 11756756 S2CID 26249687 Arias Stella J Aug 1954 Atypical endometrial changes associated with the presence of chorionic tissue Arch Pathol 58 2 112 28 PMID 13170908 Bibliography edit Textbook of Obstetrics by D C Dutta Page no 180 ISBN 81 7381 142 3 Retrieved from https en wikipedia org w index php title Arias Stella reaction amp oldid 1061830853, wikipedia, wiki, book, books, library,
