Common symptoms of ameloblastic carcinomas are pain and swelling either localized in the jaw or throughout the entire face, dysphagia, and trismus. Less common symptoms include ulceration, loosening of the teeth, chronic epistaxis, facial pressure, and nasal dyspnea.[3][4]
Causesedit
It is speculated that some cases of ameloblastic carcinoma arise from remnants of epithelial tissue left behind after the development of the teeth and related structures. Other times, it may be caused by a benign odontogenic cyst becoming malignant, or a pre-existing ameloblastoma.[5][2]
Treatmentedit
Chemotherapy has not proven effective in treating ameloblastic carcinoma, leaving surgical removal of the tumor one of the only options.[6] Surgical resection with wide margins is the main treatment.[7]
Prognosisedit
Followup after surgery is important, as over 50% of recurrences occur within 5 years.[6]
Referencesedit
^"Ameloblastic Carcinoma - NORD (National Organization for Rare Disorders)". Retrieved 2015-09-22.
^Kelly Landeen (December 2019). "A Rare Presentation of Ameloblastic Carcinoma of the Sinus Cavity and Skull Base". Cureus. 11 (12): e6265. doi:10.7759/cureus.6265. PMC6937462. PMID 31903302.
^Brad W. Neville; Douglas D. Damm; Carl M. Allen; Angela C. Chi (2019). "Odontogenic Cysts and Tumors". Color Atlas of Oral and Maxillofacial Diseases. Elsevier. pp. 411–456. doi:10.1016/B978-0-323-55225-7.00015-4. ISBN9780323552257. S2CID 239442287.
^"Ameloblastic Carcinoma - NORD (National Organization for Rare Disorders)". Retrieved 2020-12-07.
^ abP A Reichart (March 1995). "Ameloblastoma: biological profile of 3677 cases". Eur J Cancer B. 31B (2): 86–99. doi:10.1016/0964-1955(94)00037-5. PMID 7633291.
^Mahmoud, Sarah Ahmed Mohamed; Amer, Hatem Wael; Mohamed, Sally Ibrahim (2018). "Primary ameloblastic carcinoma: literature review with case series". Polish Journal of Pathology. 69 (3): 243–253. doi:10.5114/pjp.2018.79544. ISSN 1233-9687. PMID 30509051.
External linksedit
April 27, 2024
ameloblastic, carcinoma, rare, form, malignant, odontogenic, tumor, that, develops, jawbones, from, epithelial, cells, that, generate, tooth, enamel, usually, treated, with, surgery, chemotherapy, been, proven, effective, specialtyoncology, contents, signs, sy. Ameloblastic carcinoma is a rare form of malignant odontogenic tumor that develops in the jawbones from the epithelial cells that generate the tooth enamel It is usually treated with surgery chemotherapy has not been proven to be effective 1 2 Ameloblastic carcinomaSpecialtyOncology Contents 1 Signs and Symptoms 2 Causes 3 Treatment 4 Prognosis 5 References 6 External linksSigns and Symptoms editCommon symptoms of ameloblastic carcinomas are pain and swelling either localized in the jaw or throughout the entire face dysphagia and trismus Less common symptoms include ulceration loosening of the teeth chronic epistaxis facial pressure and nasal dyspnea 3 4 Causes editIt is speculated that some cases of ameloblastic carcinoma arise from remnants of epithelial tissue left behind after the development of the teeth and related structures Other times it may be caused by a benign odontogenic cyst becoming malignant or a pre existing ameloblastoma 5 2 Treatment editChemotherapy has not proven effective in treating ameloblastic carcinoma leaving surgical removal of the tumor one of the only options 6 Surgical resection with wide margins is the main treatment 7 Prognosis editFollowup after surgery is important as over 50 of recurrences occur within 5 years 6 References edit Ameloblastic Carcinoma NORD National Organization for Rare Disorders Retrieved 2015 09 22 a b Hari Ram December 2010 Ameloblastic Carcinoma J Maxillofac Oral Surg 9 4 415 419 doi 10 1007 s12663 010 0169 6 PMC 3177477 PMID 22190836 Kelly Landeen December 2019 A Rare Presentation of Ameloblastic Carcinoma of the Sinus Cavity and Skull Base Cureus 11 12 e6265 doi 10 7759 cureus 6265 PMC 6937462 PMID 31903302 Brad W Neville Douglas D Damm Carl M Allen Angela C Chi 2019 Odontogenic Cysts and Tumors Color Atlas of Oral and Maxillofacial Diseases Elsevier pp 411 456 doi 10 1016 B978 0 323 55225 7 00015 4 ISBN 9780323552257 S2CID 239442287 Ameloblastic Carcinoma NORD National Organization for Rare Disorders Retrieved 2020 12 07 a b P A Reichart March 1995 Ameloblastoma biological profile of 3677 cases Eur J Cancer B 31B 2 86 99 doi 10 1016 0964 1955 94 00037 5 PMID 7633291 Mahmoud Sarah Ahmed Mohamed Amer Hatem Wael Mohamed Sally Ibrahim 2018 Primary ameloblastic carcinoma literature review with case series Polish Journal of Pathology 69 3 243 253 doi 10 5114 pjp 2018 79544 ISSN 1233 9687 PMID 30509051 External links edit Retrieved from https en wikipedia org w index php title Ameloblastic carcinoma amp oldid 1202115701, wikipedia, wiki, book, books, library,
