Amelanotic melanoma is a type of skin cancer in which the cells do not make any melanin.[1]: 696 [2] They can be pink, red, purple or of normal skin color, and are therefore difficult to diagnose correctly. They can occur anywhere on the body, just as a typical melanoma can.
Often, amelanotic melanomas are mistaken for benign lesions, including dermatitis, benign neoplastic processes, or a different malignancy such as basal-cell carcinoma or squamous-cell carcinoma.[3] A poor prognosis is associated with amelanotic lesions, partially due to the difficulty in achieving a diagnosis; however, metastatic amelanotic melanoma has a worse prognosis than other subtypes.[3]
Survival after diagnosis of amelanotic melanoma was found in a 2014 seven-year study of 3,000 patients to be poorer than for pigmented melanoma, which was attributed to the more advanced stage at diagnosis due probably to difficulty of diagnosis. The study also suggested that amelanotic melanomas might grow faster than pigmented melanomas.[4]
^James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN978-0-7216-2921-6.
^Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN978-1-4160-2999-1.
^ abCabrera, Raúl; Recule, Francisca (2018). "Unusual Clinical Presentations of Malignant Melanoma: A Review of Clinical and Histologic Features with Special Emphasis on Dermatoscopic Findings". American Journal of Clinical Dermatology. 19 (Suppl 1): 15–23. doi:10.1007/s40257-018-0373-6. ISSN 1175-0561. PMC6244635. PMID 30374898.
^Thomas, Nancy E.; Kricker, Anne; Waxweiler, Weston T.; et al. (2014). "Comparison of Clinicopathologic Features and Survival of Histopathologically Amelanotic and Pigmented Melanomas". JAMA Dermatology. 150 (12): 1306–1314. doi:10.1001/jamadermatol.2014.1348. ISSN 2168-6068. PMC4262611. PMID 25162299.
External linksedit
Amelanotic melanoma entry in the public domain NCI Dictionary of Cancer Terms
amelanotic, melanoma, type, skin, cancer, which, cells, make, melanin, they, pink, purple, normal, skin, color, therefore, difficult, diagnose, correctly, they, occur, anywhere, body, just, typical, melanoma, toespecialtyoncology, dermatology, often, amelanoti. Amelanotic melanoma is a type of skin cancer in which the cells do not make any melanin 1 696 2 They can be pink red purple or of normal skin color and are therefore difficult to diagnose correctly They can occur anywhere on the body just as a typical melanoma can Amelanotic melanomaAmelanotic melanoma on dog s toeSpecialtyOncology dermatology Often amelanotic melanomas are mistaken for benign lesions including dermatitis benign neoplastic processes or a different malignancy such as basal cell carcinoma or squamous cell carcinoma 3 A poor prognosis is associated with amelanotic lesions partially due to the difficulty in achieving a diagnosis however metastatic amelanotic melanoma has a worse prognosis than other subtypes 3 Survival after diagnosis of amelanotic melanoma was found in a 2014 seven year study of 3 000 patients to be poorer than for pigmented melanoma which was attributed to the more advanced stage at diagnosis due probably to difficulty of diagnosis The study also suggested that amelanotic melanomas might grow faster than pigmented melanomas 4 See also editMelanoma List of cutaneous conditionsReferences edit James William D Berger Timothy G et al 2006 Andrews Diseases of the Skin clinical Dermatology Saunders Elsevier ISBN 978 0 7216 2921 6 Rapini Ronald P Bolognia Jean L Jorizzo Joseph L 2007 Dermatology 2 Volume Set St Louis Mosby ISBN 978 1 4160 2999 1 a b Cabrera Raul Recule Francisca 2018 Unusual Clinical Presentations of Malignant Melanoma A Review of Clinical and Histologic Features with Special Emphasis on Dermatoscopic Findings American Journal of Clinical Dermatology 19 Suppl 1 15 23 doi 10 1007 s40257 018 0373 6 ISSN 1175 0561 PMC 6244635 PMID 30374898 Thomas Nancy E Kricker Anne Waxweiler Weston T et al 2014 Comparison of Clinicopathologic Features and Survival of Histopathologically Amelanotic and Pigmented Melanomas JAMA Dermatology 150 12 1306 1314 doi 10 1001 jamadermatol 2014 1348 ISSN 2168 6068 PMC 4262611 PMID 25162299 External links editAmelanotic melanoma entry in the public domain NCI Dictionary of Cancer Terms nbsp This article incorporates public domain material from Dictionary of Cancer Terms U S National Cancer Institute nbsp This cutaneous condition article is a stub You can help Wikipedia by expanding it vte nbsp This oncology article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Amelanotic melanoma amp oldid 1036203002, wikipedia, wiki, book, books, library,
