6-hydroxy-3-succinoylpyridine 3-monooxygenase (EC 1.14.13.163, 6-hydroxy-3-succinoylpyridine hydroxylase, hspA (gene), hspB (gene)) is an enzyme with systematic name4-(6-hydroxypyridin-3-yl)-4-oxobutanoate,NADH:oxygen oxidoreductase (3-hydroxylating, succinate semialdehyde releasing).[1][2] This enzyme catalyses the following chemical reaction
6-hydroxy-3-succinoylpyridine 3-monooxygenase catalyses a reaction in the nicotine degradation pathway of Pseudomonas species.
Referencesedit
^Tang H, Wang S, Ma L, Meng X, Deng Z, Zhang D, Ma C, Xu P (March 2008). "A novel gene, encoding 6-hydroxy-3-succinoylpyridine hydroxylase, involved in nicotine degradation by Pseudomonas putida strain S16". Applied and Environmental Microbiology. 74 (5): 1567–74. Bibcode:2008ApEnM..74.1567T. doi:10.1128/AEM.02529-07. PMC2258644. PMID 18203859.
^Tang H, Yao Y, Zhang D, Meng X, Wang L, Yu H, Ma L, Xu P (November 2011). "A novel NADH-dependent and FAD-containing hydroxylase is crucial for nicotine degradation by Pseudomonas putida". The Journal of Biological Chemistry. 286 (45): 39179–87. doi:10.1074/jbc.M111.283929. PMC3234743. PMID 21949128.
External linksedit
6-hydroxy-3-succinoylpyridine+3-monooxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
hydroxy, succinoylpyridine, monooxygenase, hydroxy, succinoylpyridine, monooxygenase, hydroxy, succinoylpyridine, hydroxylase, hspa, gene, hspb, gene, enzyme, with, systematic, name, hydroxypyridin, oxobutanoate, nadh, oxygen, oxidoreductase, hydroxylating, su. 6 hydroxy 3 succinoylpyridine 3 monooxygenase EC 1 14 13 163 6 hydroxy 3 succinoylpyridine hydroxylase hspA gene hspB gene is an enzyme with systematic name 4 6 hydroxypyridin 3 yl 4 oxobutanoate NADH oxygen oxidoreductase 3 hydroxylating succinate semialdehyde releasing 1 2 This enzyme catalyses the following chemical reaction6 hydroxy 3 succinoylpyridine 3 monooxygenaseIdentifiersEC no 1 14 13 163DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins 4 6 hydroxypyridin 3 yl 4 oxobutanoate 2 NADH 2 H O2 displaystyle rightleftharpoons 2 5 dihydroxypyridine succinate semialdehyde 2 NAD H2O 6 hydroxy 3 succinoylpyridine 3 monooxygenase catalyses a reaction in the nicotine degradation pathway of Pseudomonas species References edit Tang H Wang S Ma L Meng X Deng Z Zhang D Ma C Xu P March 2008 A novel gene encoding 6 hydroxy 3 succinoylpyridine hydroxylase involved in nicotine degradation by Pseudomonas putida strain S16 Applied and Environmental Microbiology 74 5 1567 74 Bibcode 2008ApEnM 74 1567T doi 10 1128 AEM 02529 07 PMC 2258644 PMID 18203859 Tang H Yao Y Zhang D Meng X Wang L Yu H Ma L Xu P November 2011 A novel NADH dependent and FAD containing hydroxylase is crucial for nicotine degradation by Pseudomonas putida The Journal of Biological Chemistry 286 45 39179 87 doi 10 1074 jbc M111 283929 PMC 3234743 PMID 21949128 External links edit6 hydroxy 3 succinoylpyridine 3 monooxygenase at the U S National Library of Medicine Medical Subject Headings MeSH Portal nbsp Biology Retrieved from https en wikipedia org w index php title 6 Hydroxy 3 succinoylpyridine 3 monooxygenase amp oldid 1172337079, wikipedia, wiki, book, books, library,
