6-carboxytetrahydropterin synthase (EC 4.1.2.50, CPH4 synthase, queD (gene), ToyB , ykvK (gene)) is an enzyme with systematic name7,8-dihydroneopterin 3'-triphosphate acetaldehyde-lyase (6-carboxy-5,6,7,8-tetrahydropterin and triphosphate-forming).[1][2] This enzyme catalyses the following reversible chemical reaction.
^Cicmil N, Shi L (February 2008). "Crystallization and preliminary X-ray characterization of queD from Bacillus subtilis, an enzyme involved in queuosine biosynthesis". Acta Crystallographica Section F. 64 (2): 119–22. doi:10.1107/s1744309108000924. PMC2374184. PMID 18259064.
^ abMcCarty RM, Somogyi A, Bandarian V (March 2009). "Escherichia coli QueD is a 6-carboxy-5,6,7,8-tetrahydropterin synthase". Biochemistry. 48 (11): 2301–3. doi:10.1021/bi9001437. PMC3227869. PMID 19231875.
External linksedit
Media related to 6-carboxytetrahydropterin synthase at Wikimedia Commons
6-carboxytetrahydropterin+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
carboxytetrahydropterin, synthase, cph4, synthase, qued, gene, toyb, ykvk, gene, enzyme, with, systematic, name, dihydroneopterin, triphosphate, acetaldehyde, lyase, carboxy, tetrahydropterin, triphosphate, forming, this, enzyme, catalyses, following, reversib. 6 carboxytetrahydropterin synthase EC 4 1 2 50 CPH4 synthase queD gene ToyB ykvK gene is an enzyme with systematic name 7 8 dihydroneopterin 3 triphosphate acetaldehyde lyase 6 carboxy 5 6 7 8 tetrahydropterin and triphosphate forming 1 2 This enzyme catalyses the following reversible chemical reaction 6 carboxytetrahydropterin synthase6 Carboxy 5 6 7 8 tetrahydropterin synthase hexamer E ColiIdentifiersEC no 4 1 2 50DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins 7 8 dihydroneopterin 3 triphosphate H2O 6 carboxy 5 6 7 8 tetrahydropterin acetaldehyde triphosphate This enzyme binds Zn2 It is isolated from the bacteria Bacillus subtilis and Escherichia coli The stimulation is part of the biosynthesis pathway of queuosine The enzyme from Escherichia coli can also convert 6 pyruvoyl 5 6 7 8 tetrahydropterin and sepiapterin to 6 carboxy 5 6 7 8 tetrahydropterin 2 References edit Cicmil N Shi L February 2008 Crystallization and preliminary X ray characterization of queD from Bacillus subtilis an enzyme involved in queuosine biosynthesis Acta Crystallographica Section F 64 2 119 22 doi 10 1107 s1744309108000924 PMC 2374184 PMID 18259064 a b McCarty RM Somogyi A Bandarian V March 2009 Escherichia coli QueD is a 6 carboxy 5 6 7 8 tetrahydropterin synthase Biochemistry 48 11 2301 3 doi 10 1021 bi9001437 PMC 3227869 PMID 19231875 External links edit nbsp Media related to 6 carboxytetrahydropterin synthase at Wikimedia Commons 6 carboxytetrahydropterin synthase at the U S National Library of Medicine Medical Subject Headings MeSH Portal nbsp Biology Retrieved from https en wikipedia org w index php title 6 carboxytetrahydropterin synthase amp oldid 1172337059, wikipedia, wiki, book, books, library,
