This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is 4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating). Other names in common use include 4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine, dinucleotide (phosphate)), 4-hydroxybenzoate-3-hydroxylase, and 4-hydroxybenzoate 3-hydroxylase. This enzyme participates in benzoate degradation via hydroxylation and 2,4-dichlorobenzoate degradation. It employs one cofactor, FAD.
Referencesedit
Fujii T, Kaneda T (1985). "Purification and properties of NADH/NADPH-dependent p-hydroxybenzoate hydroxylase from Corynebacterium cyclohexanicum". Eur. J. Biochem. 147 (1): 97–104. doi:10.1111/j.1432-1033.1985.tb08724.x. PMID 3971979.
Seibold B, Matthes M, Eppink MH, Lingens F, Van Berkel WJ, Muller R (1996). "4-Hydroxybenzoate hydroxylase from Pseudomonas sp. CBS3 Purification, characterization, gene cloning, sequence analysis and assignment of structural features determining the coenzyme specificity". Eur. J. Biochem. 239 (2): 469–78. doi:10.1111/j.1432-1033.1996.0469u.x. PMID 8706756.
hydroxybenzoate, monooxygenase, enzymology, hydroxybenzoate, monooxygenase, enzyme, that, catalyzes, chemical, reaction4, hydroxybenzoate, monooxygenase, identifiersec, 33cas, 95471, 3databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, . In enzymology a 4 hydroxybenzoate 3 monooxygenase NAD P H EC 1 14 13 33 is an enzyme that catalyzes the chemical reaction4 hydroxybenzoate 3 monooxygenase NAD P H IdentifiersEC no 1 14 13 33CAS no 95471 33 3DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins 4 hydroxybenzoate NAD P H H O2 displaystyle rightleftharpoons 3 4 dihydroxybenzoate NAD P H2OThe 5 substrates of this enzyme are 4 hydroxybenzoate NADH NADPH H and O2 whereas its 4 products are 3 4 dihydroxybenzoate NAD NADP and H2O This enzyme belongs to the family of oxidoreductases specifically those acting on paired donors with O2 as oxidant and incorporation or reduction of oxygen The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor and incorporation of one atom o oxygen into the other donor The systematic name of this enzyme class is 4 hydroxybenzoate NAD P H oxygen oxidoreductase 3 hydroxylating Other names in common use include 4 hydroxybenzoate 3 monooxygenase reduced nicotinamide adenine dinucleotide phosphate 4 hydroxybenzoate 3 hydroxylase and 4 hydroxybenzoate 3 hydroxylase This enzyme participates in benzoate degradation via hydroxylation and 2 4 dichlorobenzoate degradation It employs one cofactor FAD References editFujii T Kaneda T 1985 Purification and properties of NADH NADPH dependent p hydroxybenzoate hydroxylase from Corynebacterium cyclohexanicum Eur J Biochem 147 1 97 104 doi 10 1111 j 1432 1033 1985 tb08724 x PMID 3971979 Seibold B Matthes M Eppink MH Lingens F Van Berkel WJ Muller R 1996 4 Hydroxybenzoate hydroxylase from Pseudomonas sp CBS3 Purification characterization gene cloning sequence analysis and assignment of structural features determining the coenzyme specificity Eur J Biochem 239 2 469 78 doi 10 1111 j 1432 1033 1996 0469u x PMID 8706756 Portal nbsp Biology This EC 1 14 13 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title 4 hydroxybenzoate 3 monooxygenase NAD P H amp oldid 1172336409, wikipedia, wiki, book, books, library,
