Thus, the two substrates of this enzyme are 3beta-hydroxy-5beta-pregnane-20-one and NADP+, whereas its 3 products are 5beta-pregnan-3,20-dione, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase. Other names in common use include 3beta-hydroxysteroid 5beta-oxidoreductase, and 3beta-hydroxysteroid 5beta-progesterone oxidoreductase.
Referencesedit
Stuhlemmer U, Kreis W (1996). "Cardenolide formation and activity of pregnane-modifying enzymes in cell suspension cultures, shoot cultures and leaves of Digitalis lanata". Plant Physiol. Biochem. 34: 85–91.
Seitz HU, Gaertner DE (1994). "Enzymes in cardenolide-accumulating shoot cultures of Digitalis purpurea". Plant Cell. 38: 337–344. doi:10.1007/bf00033894.
Lindemann P, Luckner M (1997). "Biosynthesis of pregnane derivatives in somatic embryos of Digitalis lanata". Phytochemistry. 46 (3): 507–513. doi:10.1016/S0031-9422(97)00315-4.
3beta, hydroxy, 5beta, steroid, dehydrogenase, enzymology, enzyme, that, catalyzes, chemical, reactionidentifiersec, 277databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic, pathwaypriamprofilepdb, structuresrcsb, p. In enzymology a 3beta hydroxy 5beta steroid dehydrogenase EC 1 1 1 277 is an enzyme that catalyzes the chemical reaction3beta hydroxy 5beta steroid dehydrogenaseIdentifiersEC no 1 1 1 277DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins 3beta hydroxy 5beta pregnane 20 one NADP displaystyle rightleftharpoons 5beta pregnan 3 20 dione NADPH H Thus the two substrates of this enzyme are 3beta hydroxy 5beta pregnane 20 one and NADP whereas its 3 products are 5beta pregnan 3 20 dione NADPH and H This enzyme belongs to the family of oxidoreductases specifically those acting on the CH OH group of donor with NAD or NADP as acceptor The systematic name of this enzyme class is 3beta hydroxy 5beta steroid NADP 3 oxidoreductase Other names in common use include 3beta hydroxysteroid 5beta oxidoreductase and 3beta hydroxysteroid 5beta progesterone oxidoreductase References editStuhlemmer U Kreis W 1996 Cardenolide formation and activity of pregnane modifying enzymes in cell suspension cultures shoot cultures and leaves of Digitalis lanata Plant Physiol Biochem 34 85 91 Seitz HU Gaertner DE 1994 Enzymes in cardenolide accumulating shoot cultures of Digitalis purpurea Plant Cell 38 337 344 doi 10 1007 bf00033894 Lindemann P Luckner M 1997 Biosynthesis of pregnane derivatives in somatic embryos of Digitalis lanata Phytochemistry 46 3 507 513 doi 10 1016 S0031 9422 97 00315 4 Portal nbsp Biology This EC 1 1 1 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title 3beta hydroxy 5beta steroid dehydrogenase amp oldid 1172336179, wikipedia, wiki, book, books, library,
