Thus, the two substrates of this enzyme are (S)-2-hydroxymethylglutarate and NAD+, whereas its 3 products are 2-formylglutarate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-2-hydroxymethylglutarate:NAD+ oxidoreductase. This enzyme is also called HgD.
Referencesedit
Alhapel A, Darley DJ, Wagener N, Eckel E, Elsner N, Pierik AJ (2006). "Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri". Proc. Natl. Acad. Sci. U.S.A. 103 (33): 12341–6. Bibcode:2006PNAS..10312341A. doi:10.1073/pnas.0601635103. PMC1562527. PMID 16894175.
hydroxymethylglutarate, dehydrogenase, enzymology, enzyme, that, catalyzes, chemical, reactionidentifiersec, 291databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic, pathwaypriamprofilepdb, structuresrcsb, pdbe, pdb. In enzymology a 2 hydroxymethylglutarate dehydrogenase EC 1 1 1 291 is an enzyme that catalyzes the chemical reaction2 hydroxymethylglutarate dehydrogenaseIdentifiersEC no 1 1 1 291DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins S 2 hydroxymethylglutarate NAD displaystyle rightleftharpoons 2 formylglutarate NADH H Thus the two substrates of this enzyme are S 2 hydroxymethylglutarate and NAD whereas its 3 products are 2 formylglutarate NADH and H This enzyme belongs to the family of oxidoreductases specifically those acting on the CH OH group of donor with NAD or NADP as acceptor The systematic name of this enzyme class is S 2 hydroxymethylglutarate NAD oxidoreductase This enzyme is also called HgD References editAlhapel A Darley DJ Wagener N Eckel E Elsner N Pierik AJ 2006 Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri Proc Natl Acad Sci U S A 103 33 12341 6 Bibcode 2006PNAS 10312341A doi 10 1073 pnas 0601635103 PMC 1562527 PMID 16894175 Portal nbsp Biology This EC 1 1 1 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title 2 hydroxymethylglutarate dehydrogenase amp oldid 1172334914, wikipedia, wiki, book, books, library,
