This enzyme belongs to the family of hydrolases, to be specific, those acting on phosphoric monoester bonds. The systematic name is 2-carboxy-D-arabinitol-1-phosphate 1-phosphohydrolase.
In biologyEdit
The best-studied 2-Carboxy-D-arabinitol-1-phosphate phosphatase is the enzyme that inactivates the RuBisCO inhibitor 2-carboxy-D-arabinitol-1-phosphate (CA1P).
When light levels are high, the inactivation occurs after CA1P has been released from RuBisCO by RuBisCO activase. As CA1P is present in many but not all plants, CA1P-mediated regulation of RuBisCO is not universal for all photosynthetic life. Amino acid sequences of the CA1Pase enzymes from wheat, French bean, tobacco, and Arabidopsis thaliana reveal that the enzymes contain 2 different domains, indicating that it is a multifunctional enzyme.
CA1Pase enzyme activity varies between different species due to their regulation by different redox-active compounds, such as glutathione. However, it is yet to be determined whether this process occurs in vivo. Wheat CA1Pase heterologously expressed in E. coli is also able to dephosphorylate the RuBisCO inhibitor D-glycero-2,3-diulose-1,5-bisphosphate.[1]
ReferencesEdit
^Andralojc PJ, Madgwick PJ, Tao Y, Keys A, Ward JL, Beale MH, et al. (March 2012). "2-Carboxy-D-arabinitol 1-phosphate (CA1P) phosphatase: evidence for a wider role in plant Rubisco regulation". The Biochemical Journal. 442 (3): 733–42. doi:10.1042/BJ20111443. PMID 22132794.
Further readingEdit
Salvucci ME, Holbrook GP (June 1989). "Purification and Properties of 2-Carboxy-D-Arabinitol 1-Phosphatase". Plant Physiology. 90 (2): 679–85. doi:10.1104/pp.90.2.679. PMC1061780. PMID 16666827.
carboxy, arabinitol, phosphatase, enzyme, carboxy, arabinitol, phosphatase, ca1pase, catalyzes, reactionidentifiersec, 63cas, 122319, 4databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg, entrymetacycmetabolic, pathwaypriamprofilepdb, st. The enzyme 2 carboxy D arabinitol 1 phosphatase CA1Pase EC 3 1 3 63 catalyzes the reaction2 Carboxy D arabinitol 1 phosphataseIdentifiersEC no 3 1 3 63CAS no 122319 88 4DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins 2 carboxy D arabinitol 1 phosphate H2O displaystyle rightleftharpoons 2 carboxy D arabinitol phosphateThis enzyme belongs to the family of hydrolases to be specific those acting on phosphoric monoester bonds The systematic name is 2 carboxy D arabinitol 1 phosphate 1 phosphohydrolase In biology EditThe best studied 2 Carboxy D arabinitol 1 phosphate phosphatase is the enzyme that inactivates the RuBisCO inhibitor 2 carboxy D arabinitol 1 phosphate CA1P When light levels are high the inactivation occurs after CA1P has been released from RuBisCO by RuBisCO activase As CA1P is present in many but not all plants CA1P mediated regulation of RuBisCO is not universal for all photosynthetic life Amino acid sequences of the CA1Pase enzymes from wheat French bean tobacco and Arabidopsis thaliana reveal that the enzymes contain 2 different domains indicating that it is a multifunctional enzyme CA1Pase enzyme activity varies between different species due to their regulation by different redox active compounds such as glutathione However it is yet to be determined whether this process occurs in vivo Wheat CA1Pase heterologously expressed in E coli is also able to dephosphorylate the RuBisCO inhibitor D glycero 2 3 diulose 1 5 bisphosphate 1 References Edit Andralojc PJ Madgwick PJ Tao Y Keys A Ward JL Beale MH et al March 2012 2 Carboxy D arabinitol 1 phosphate CA1P phosphatase evidence for a wider role in plant Rubisco regulation The Biochemical Journal 442 3 733 42 doi 10 1042 BJ20111443 PMID 22132794 Further reading EditSalvucci ME Holbrook GP June 1989 Purification and Properties of 2 Carboxy D Arabinitol 1 Phosphatase Plant Physiology 90 2 679 85 doi 10 1104 pp 90 2 679 PMC 1061780 PMID 16666827 Portal Biology This EC 3 1 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title 2 Carboxy D arabinitol 1 phosphatase amp oldid 1165190037, wikipedia, wiki, book, books, library,
