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2,4-Dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2 -D-glucosyltransferase

2,4-Dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase (EC 2.4.1.202, uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase, BX8, BX9, benzoxazinoid glucosyltransferase, DIMBOA glucosyltransferase) is an enzyme with systematic name UDP-alpha-D-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-beta-D-glucosyltransferase.[1][2] This enzyme catalyses the following chemical reaction

2,4-Dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase
Identifiers
EC no.2.4.1.202
CAS no.122544-56-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
(1) UDP-alpha-D-glucose + 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one UDP + (2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside
(2) UDP-alpha-D-glucose + 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one UDP + (2R)-4-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside

The enzyme is involved in the detoxification of the benzoxazinoids, DIBOA (2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one) and DIMBOA (2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one).

References edit

  1. ^ Bailey BA, Larson RL (July 1989). "Hydroxamic Acid glucosyltransferases from maize seedlings". Plant Physiology. 90 (3): 1071–6. doi:10.1104/pp.90.3.1071. PMC 1061845. PMID 16666853.
  2. ^ von Rad U, Hüttl R, Lottspeich F, Gierl A, Frey M (December 2001). "Two glucosyltransferases are involved in detoxification of benzoxazinoids in maize". The Plant Journal. 28 (6): 633–42. doi:10.1046/j.1365-313x.2001.01161.x. PMID 11851909.

External links edit

  • 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one+2-D-glucosyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

dihydroxy, methoxy, benzoxazin, glucosyltransferase, dihydroxy, methoxy, benzoxazin, glucosyltransferase, uridine, diphosphoglucose, dihydroxy, methoxy, benzoxazin, glucosyltransferase, benzoxazinoid, glucosyltransferase, dimboa, glucosyltransferase, enzyme, w. 2 4 Dihydroxy 7 methoxy 2H 1 4 benzoxazin 3 4H one 2 D glucosyltransferase EC 2 4 1 202 uridine diphosphoglucose 2 4 dihydroxy 7 methoxy 2H 1 4 benzoxazin 3 4H one 2 glucosyltransferase BX8 BX9 benzoxazinoid glucosyltransferase DIMBOA glucosyltransferase is an enzyme with systematic name UDP alpha D glucose 2 4 dihydroxy 7 methoxy 2H 1 4 benzoxazin 3 4H one 2 beta D glucosyltransferase 1 2 This enzyme catalyses the following chemical reaction2 4 Dihydroxy 7 methoxy 2H 1 4 benzoxazin 3 4H one 2 D glucosyltransferaseIdentifiersEC no 2 4 1 202CAS no 122544 56 3DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumSearchPMCarticlesPubMedarticlesNCBIproteins 1 UDP alpha D glucose 2 4 dihydroxy 7 methoxy 2H 1 4 benzoxazin 3 4H one displaystyle rightleftharpoons UDP 2R 4 hydroxy 7 methoxy 3 oxo 3 4 dihydro 2H 1 4 benzoxazin 2 yl beta D glucopyranoside 2 UDP alpha D glucose 2 4 dihydroxy 2H 1 4 benzoxazin 3 4H one displaystyle rightleftharpoons UDP 2R 4 hydroxy 3 oxo 3 4 dihydro 2H 1 4 benzoxazin 2 yl beta D glucopyranoside The enzyme is involved in the detoxification of the benzoxazinoids DIBOA 2 4 dihydroxy 2H 1 4 benzoxazin 3 4H one and DIMBOA 2 4 dihydroxy 7 methoxy 2H 1 4 benzoxazin 3 4H one References edit Bailey BA Larson RL July 1989 Hydroxamic Acid glucosyltransferases from maize seedlings Plant Physiology 90 3 1071 6 doi 10 1104 pp 90 3 1071 PMC 1061845 PMID 16666853 von Rad U Huttl R Lottspeich F Gierl A Frey M December 2001 Two glucosyltransferases are involved in detoxification of benzoxazinoids in maize The Plant Journal 28 6 633 42 doi 10 1046 j 1365 313x 2001 01161 x PMID 11851909 External links edit2 4 dihydroxy 7 methoxy 2H 1 4 benzoxazin 3 4H one 2 D glucosyltransferase at the U S National Library of Medicine Medical Subject Headings MeSH Portal nbsp Biology Retrieved from https en wikipedia org w index php title 2 4 Dihydroxy 7 methoxy 2H 1 4 benzoxazin 3 4H one 2 D glucosyltransferase amp oldid 1172335297, wikipedia, wiki, book, books, library,

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