This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name is holo-[acyl-carrier-protein] 4′-pantetheine-phosphohydrolase. Other names in common use include ACP hydrolyase, ACP phosphodiesterase, AcpH, and [acyl-carrier-protein] 4′-pantetheine-phosphohydrolase. This enzyme participates in pantothenate and CoA biosynthesis.
Structural studiesedit
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1T5B and 1TIK.
Referencesedit
Sobhy C (1979). "Regulation of fatty acid synthetase activity. The 4′-phosphopantetheine hydrolase of rat liver". J. Biol. Chem. 254 (17): 8561–6. PMID 224058.
Vagelos PR, Larrabes AR (1967). "Acyl carrier protein. IX. Acyl carrier protein hydrolase". J. Biol. Chem. 242 (8): 1776–81. PMID 4290442.
Thomas J, Cronan JE (2005). "The enigmatic acyl carrier protein phosphodiesterase of Escherichia coli: genetic and enzymological characterization". J. Biol. Chem. 280 (41): 34675–83. doi:10.1074/jbc.M505736200. PMID 16107329.
acyl, carrier, protein, phosphodiesterase, enzyme, acyl, carrier, protein, phosphodiesterase, catalyzes, reaction, acyl, carrier, protein, phosphodiesteraseidentifiersec, 14cas, 37288, 4databasesintenzintenz, viewbrendabrenda, entryexpasynicezyme, viewkeggkegg. The enzyme acyl carrier protein phosphodiesterase EC 3 1 4 14 catalyzes the reaction acyl carrier protein phosphodiesteraseIdentifiersEC no 3 1 4 14CAS no 37288 21 4DatabasesIntEnzIntEnz viewBRENDABRENDA entryExPASyNiceZyme viewKEGGKEGG entryMetaCycmetabolic pathwayPRIAMprofilePDB structuresRCSB PDB PDBe PDBsumGene OntologyAmiGO QuickGOSearchPMCarticlesPubMedarticlesNCBIproteins holo acyl carrier protein H2O displaystyle rightleftharpoons 4 phosphopantetheine apo acyl carrier protein This enzyme belongs to the family of hydrolases specifically those acting on phosphoric diester bonds The systematic name is holo acyl carrier protein 4 pantetheine phosphohydrolase Other names in common use include ACP hydrolyase ACP phosphodiesterase AcpH and acyl carrier protein 4 pantetheine phosphohydrolase This enzyme participates in pantothenate and CoA biosynthesis Structural studies editAs of late 2007 two structures have been solved for this class of enzymes with PDB accession codes 1T5B and 1TIK References editSobhy C 1979 Regulation of fatty acid synthetase activity The 4 phosphopantetheine hydrolase of rat liver J Biol Chem 254 17 8561 6 PMID 224058 Vagelos PR Larrabes AR 1967 Acyl carrier protein IX Acyl carrier protein hydrolase J Biol Chem 242 8 1776 81 PMID 4290442 Thomas J Cronan JE 2005 The enigmatic acyl carrier protein phosphodiesterase of Escherichia coli genetic and enzymological characterization J Biol Chem 280 41 34675 83 doi 10 1074 jbc M505736200 PMID 16107329 Portal nbsp Biology This EC 3 1 enzyme related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title acyl carrier protein phosphodiesterase amp oldid 1195284320, wikipedia, wiki, book, books, library,
