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Frank Fenner

Frank John Fenner AC CMG MBE FRS FAA (21 December 1914 – 22 November 2010) was an Australian scientist with a distinguished career in the field of virology. His two greatest achievements are cited as overseeing the eradication of smallpox,[2] and the attempted control of Australia's rabbit plague through the introduction of Myxoma virus.[3]

Frank Fenner

Born
Frank Johannes Fenner

21 December 1914
Died22 November 2010(2010-11-22) (aged 95)[1]
NationalityAustralian
Other namesFrank John Fenner (after 1938)
EducationUniversity of Adelaide
OccupationVirology
EmployerAustralian National University
Known forEradication of smallpox
Control of Australia's rabbit plague
SpouseEllen Margaret Bobbie Roberts
Parent(s)Albert Charles Fenner and Emma Louise "Peggy" Hirt

The Australian Academy of Science awards annually the prestigious Fenner Medal for distinguished research in biology by a scientist under 40 years of age.[4][5]

Early life and education edit

Frank Johannes Fenner was born in Ballarat in 1914. The family moved to Adelaide, South Australia in November 1916. He attended Rose Park Primary School and Thebarton Technical School. He attended the University of Adelaide, where he earned degrees in medicine and surgery in 1938. That year, uneasy about Hitler's rise, he legally changed his middle name to John.[6]

Career edit

In May 1937, Fenner was a member of an Adelaide University anthropological expedition to Nepabunna Mission in the northern Flinders Ranges in South Australia led by J.B. Cleland, which also included Charles P. Mountford as ethnologist and photographer, as well as botanist Thomas Harvey Johnston, and others.[7]

From 1940 to 1946 he was a Captain and Major in the Australian Army Medical Corps with service in Australia, Palestine, Egypt, New Guinea, and Borneo,[6] as medical officer in field ambulance and Casualty Clearing Station, pathologist to general hospital, and malariologist. For his work in combating malaria in Papua New Guinea he was made a Member of the Order of the British Empire in 1945.[8][9]

Following his war-time service he was recruited by Frank Macfarlane Burnet to work at the Walter and Eliza Hall Institute of Medical Research in Melbourne. Initially they worked on smallpox in mice, for which he coined the term "mousepox", and later on the genetics of poxvirus.

In 1949, he received a fellowship to study at the Rockefeller Institute for Medical Research in New York City, he worked on mycobacterium Bairnsdale bacillus, which causes Buruli ulcer, the third most important mycobacterial disease worldwide after tuberculosis and leprosy. Here he worked with and was influenced by René Dubos, who is one of the claimed originators of the phrase "Think Globally, Act Locally".[citation needed]

In Canberra, 1949–2010 edit

Returning to Australia in 1949, he was appointed professor of microbiology at the new John Curtin School of Medical Research at the Australian National University, Canberra. Here he began studying viruses again, in particular the myxoma virus.

Throughout the 1940s and 1950s Australia had severe rabbit plagues. Fenner's work on the myxoma virus showed that initially it killed rabbits in 9 to 11 days and was 99.5% lethal. Under heavy selection pressure, the few rabbits that survived developed resistance, which meant that the pest was never completely eradicated, but their numbers were reduced. Prior to the release of the virus as a biological control for the rabbits, Fenner, Frank Macfarlane Burnet, and Ian Clunies Ross famously injected themselves with myxoma virus, to prove it was not dangerous for humans.

From 1967 to 1973 Fenner was Director of the John Curtin School of Medical Research. In 1977, he was named the chairman of the Global Commission for the Certification of Smallpox Eradication, the same year the last known case of naturally transmitted smallpox occurred in Somalia. Fenner announced the eradication of smallpox to the World Health Assembly on 8 May 1980.[6] This success story is regarded as the greatest achievement of the World Health Organization. Before its eradication, smallpox was one of the world's most virulent viruses, responsible for millions of deaths, and leaving many of the victims who survived with disfiguring scars for life.

Fenner had an abiding interest in the environment, and was the foundation Director of the Centre for Resources and Environmental Studies at the ANU (1973), where he worked until his retirement in 1979, and which became part of the Fenner School of Environment and Society in 2007.[10] He was a keen supporter of Australia having an ecologically, socially sustainable population. He was emeritus professor at the John Curtin School of Medical Research.

In June 2010, he predicted in an interview with The Australian the extinction of the human race within a century, primarily as the result of human overpopulation, environmental degradation and climate change.[6][11][12]

He died in Canberra on the morning of 22 November 2010 after a brief illness, and days after the birth of his first great-grandchild.[13]

Personal life edit

In 1944 Fenner met Bobbie Roberts. Ellen Margaret 'Bobbie' Roberts was a trained midwife and nurse. During World War II she worked on malaria with the Australian Army Nursing Service and through her work met Fenner.[14] Shortly after they met they married in a Catholic ceremony (despite Fenner being an atheist).[15] While keen to have children, the couple were infertile and with Bobbie having a hysterectomy in 1949 they decided to adopt. They subsequently adopted two children. Marilyn Aldus Fenner was born on 27 June 1950. Her biological parents were unknown. Victoria Fenner (born 1 March 1943) was adopted later at the request of her father (Fenner's younger brother Tom) after the death in a fire of Victoria's mother (Beverley Slaney).[16]

On 30 March 1958, Victoria Fenner shot and killed herself, with the assistance of another child, Catherine Webb. The coronial inquiry heard she had been passing through a period of extreme mental and spiritual disturbance and the coroner declared her death a suicide.[17] Fenner himself was unable to fathom a motive, other than she was upset from reading Neville Shute's book, On the Beach.[18]

Bobbie Fenner was diagnosed with cancer in 1989 and eventually died in 1994. Marilyn Fenner and her family then moved into the family home and looked after her father until his death.[19]

Publications edit

  • Frank Fenner and Francis Ratcliffe, Myxmatosis. Cambridge University Press, 1965. ISBN 0521049911
  • Fenner, Frank; Wittek, Riccardo; Dumbell, Keith R. (1988). The Orthopoxviruses. Elsevier. ISBN 978-0-323-15022-4.

Honours edit

Of the many honours Fenner received throughout his career, there are the following:

References edit

  1. ^ Henderson, Donald A. (2011). "Frank Fenner (1914–2010) A guiding light of the campaign to eradicate smallpox". Nature. 469 (7328): 35. doi:10.1038/469035a. PMID 21209651.
  2. ^ Frank F. Fenner, Donald A. Henderson, Isao Arita, Zdeněk Ježek, Ivan D. Ladnyi Smallpox and its Eradication World Health Organization Geneva, 1988
  3. ^ Boyden, S.; Blanden, R.; Mims, C. (2013). "Frank John Fenner FAA. 21 December 1914 -- 22 November 2010". Biographical Memoirs of Fellows of the Royal Society. 59: 125–144. doi:10.1098/rsbm.2013.0009. hdl:1885/65529. S2CID 71415413.
  4. ^ "Australian Academy of Science – Fenner medal". Archived from the original on 13 April 2014. Retrieved 13 April 2014.
  5. ^ "UWA scientist wins Academy Award".
  6. ^ a b c d Grimes, William (25 November 2010). "Frank Fenner Dies at 95; Tracked End of Smallpox". The New York Times.
  7. ^ "Nepabunna, 1937–39". SA Memory. State Library of South Australia. 28 October 2009. Retrieved 13 November 2020.
  8. ^ a b It's an Honour: MBE
  9. ^ a b Citation record of MBE [1]
  10. ^ Fenner School of Environment and Society website
  11. ^ Jones, Cheryl (15 June 2010). "Fenner sees no hope for humans". The Australian.
  12. ^ Edwards, Lin (23 June 2010). "Humans will be extinct in 100 years says eminent scientist". Phys.org. Retrieved 2 July 2020.
  13. ^ "Scientist Fenner dies aged 95". Australian Broadcasting Corporation. 22 November 2010.
  14. ^ Encyclopaedia of Australian Science
  15. ^ Chapter 3, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  16. ^ Chapter 5, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  17. ^ Suicide Finding in Death of Girl 15 in Canberra, Sydney Morning Herald, 20 June 1958, p3
  18. ^ Chapter 5, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  19. ^ Chapter 11, Nature, Nurture and Chance: the lives of Frank and Charles Fenner
  20. ^ It's an Honour: CMG
  21. ^ "Macfarlane Burnet Medal and Lecture". Australian Academy of Science. Retrieved 22 February 2017.
  22. ^ It's an Honour: AC
  23. ^ . Archived from the original on 29 July 2013. Retrieved 14 August 2013.
  24. ^ "Jon Stanhope appalled by ACT federal seat renamed from Fraser to Fenner". 24 November 2015.
  25. ^ "Voters call out AEC on Fraser electorate renaming". 19 October 2015.

External links edit

  • Australian Academy of Science—Interview with Professor Frank Fenner
  • Australian War Memorial Honours and Awards Database[permanent dead link]
  • Stephen Boyden; Robert Blanden; Cedric Mims. "Frank John Fenner 1914–2010" (PDF). Biographical memoirs. Australian Academy of Science. Originally published in Historical Records of Australian Science, vol.24, no.1, pp. 109–133, 2013.

frank, fenner, frank, john, fenner, december, 1914, november, 2010, australian, scientist, with, distinguished, career, field, virology, greatest, achievements, cited, overseeing, eradication, smallpox, attempted, control, australia, rabbit, plague, through, i. Frank John Fenner AC CMG MBE FRS FAA 21 December 1914 22 November 2010 was an Australian scientist with a distinguished career in the field of virology His two greatest achievements are cited as overseeing the eradication of smallpox 2 and the attempted control of Australia s rabbit plague through the introduction of Myxoma virus 3 Frank FennerAC CMG MBE FRS FAABornFrank Johannes Fenner21 December 1914BallaratDied22 November 2010 2010 11 22 aged 95 1 CanberraNationalityAustralianOther namesFrank John Fenner after 1938 EducationUniversity of AdelaideOccupationVirologyEmployerAustralian National UniversityKnown forEradication of smallpoxControl of Australia s rabbit plagueSpouseEllen Margaret Bobbie RobertsParent s Albert Charles Fenner and Emma Louise Peggy HirtThe Australian Academy of Science awards annually the prestigious Fenner Medal for distinguished research in biology by a scientist under 40 years of age 4 5 Contents 1 Early life and education 2 Career 2 1 In Canberra 1949 2010 3 Personal life 4 Publications 5 Honours 6 References 7 External linksEarly life and education editFrank Johannes Fenner was born in Ballarat in 1914 The family moved to Adelaide South Australia in November 1916 He attended Rose Park Primary School and Thebarton Technical School He attended the University of Adelaide where he earned degrees in medicine and surgery in 1938 That year uneasy about Hitler s rise he legally changed his middle name to John 6 Career editIn May 1937 Fenner was a member of an Adelaide University anthropological expedition to Nepabunna Mission in the northern Flinders Ranges in South Australia led by J B Cleland which also included Charles P Mountford as ethnologist and photographer as well as botanist Thomas Harvey Johnston and others 7 From 1940 to 1946 he was a Captain and Major in the Australian Army Medical Corps with service in Australia Palestine Egypt New Guinea and Borneo 6 as medical officer in field ambulance and Casualty Clearing Station pathologist to general hospital and malariologist For his work in combating malaria in Papua New Guinea he was made a Member of the Order of the British Empire in 1945 8 9 Following his war time service he was recruited by Frank Macfarlane Burnet to work at the Walter and Eliza Hall Institute of Medical Research in Melbourne Initially they worked on smallpox in mice for which he coined the term mousepox and later on the genetics of poxvirus In 1949 he received a fellowship to study at the Rockefeller Institute for Medical Research in New York City he worked on mycobacterium Bairnsdale bacillus which causes Buruli ulcer the third most important mycobacterial disease worldwide after tuberculosis and leprosy Here he worked with and was influenced by Rene Dubos who is one of the claimed originators of the phrase Think Globally Act Locally citation needed In Canberra 1949 2010 edit Returning to Australia in 1949 he was appointed professor of microbiology at the new John Curtin School of Medical Research at the Australian National University Canberra Here he began studying viruses again in particular the myxoma virus Throughout the 1940s and 1950s Australia had severe rabbit plagues Fenner s work on the myxoma virus showed that initially it killed rabbits in 9 to 11 days and was 99 5 lethal Under heavy selection pressure the few rabbits that survived developed resistance which meant that the pest was never completely eradicated but their numbers were reduced Prior to the release of the virus as a biological control for the rabbits Fenner Frank Macfarlane Burnet and Ian Clunies Ross famously injected themselves with myxoma virus to prove it was not dangerous for humans From 1967 to 1973 Fenner was Director of the John Curtin School of Medical Research In 1977 he was named the chairman of the Global Commission for the Certification of Smallpox Eradication the same year the last known case of naturally transmitted smallpox occurred in Somalia Fenner announced the eradication of smallpox to the World Health Assembly on 8 May 1980 6 This success story is regarded as the greatest achievement of the World Health Organization Before its eradication smallpox was one of the world s most virulent viruses responsible for millions of deaths and leaving many of the victims who survived with disfiguring scars for life Fenner had an abiding interest in the environment and was the foundation Director of the Centre for Resources and Environmental Studies at the ANU 1973 where he worked until his retirement in 1979 and which became part of the Fenner School of Environment and Society in 2007 10 He was a keen supporter of Australia having an ecologically socially sustainable population He was emeritus professor at the John Curtin School of Medical Research In June 2010 he predicted in an interview with The Australian the extinction of the human race within a century primarily as the result of human overpopulation environmental degradation and climate change 6 11 12 He died in Canberra on the morning of 22 November 2010 after a brief illness and days after the birth of his first great grandchild 13 Personal life editIn 1944 Fenner met Bobbie Roberts Ellen Margaret Bobbie Roberts was a trained midwife and nurse During World War II she worked on malaria with the Australian Army Nursing Service and through her work met Fenner 14 Shortly after they met they married in a Catholic ceremony despite Fenner being an atheist 15 While keen to have children the couple were infertile and with Bobbie having a hysterectomy in 1949 they decided to adopt They subsequently adopted two children Marilyn Aldus Fenner was born on 27 June 1950 Her biological parents were unknown Victoria Fenner born 1 March 1943 was adopted later at the request of her father Fenner s younger brother Tom after the death in a fire of Victoria s mother Beverley Slaney 16 On 30 March 1958 Victoria Fenner shot and killed herself with the assistance of another child Catherine Webb The coronial inquiry heard she had been passing through a period of extreme mental and spiritual disturbance and the coroner declared her death a suicide 17 Fenner himself was unable to fathom a motive other than she was upset from reading Neville Shute s book On the Beach 18 Bobbie Fenner was diagnosed with cancer in 1989 and eventually died in 1994 Marilyn Fenner and her family then moved into the family home and looked after her father until his death 19 Publications editFrank Fenner and Francis Ratcliffe Myxmatosis Cambridge University Press 1965 ISBN 0521049911 Fenner Frank Wittek Riccardo Dumbell Keith R 1988 The Orthopoxviruses Elsevier ISBN 978 0 323 15022 4 Honours editOf the many honours Fenner received throughout his career there are the following Member of the Order of the British Empire MBE 19 July 1945 8 9 Companion of the Order of St Michael and St George CMG 12 June 1976 in recognition of service to medical research 20 The Macfarlane Burnet Medal and Lecture of the Australian Academy of Science 1985 21 The Japan Prize Preventive Medicine 1988 with Donald Henderson and Isao Arita Companion of the Order of Australia AC 26 January 1989 in recognition of service to medical science to public health and to the environment 22 Copley medal of the Royal Society 1995 Albert Einstein World Award of Science 2000 23 Clunies Ross Lifetime Contribution National Science and Technology Award 2002 Both the Frank Fenner building which houses the ANU Medical School and Faculty of Science and a residential college Fenner Hall are named in honour of Frank Fenner WHO Medal Mueller Medal 1964 and ANZAAS Medal 1980 ANZAC Peace Prize Matthew Flinders Medal and Lecture 1967 Britannica Australia Award for Medicine 2002 Prime Minister s Prize for Science ACT Senior Australian of the Year 2005 The federal Division of Fraser named for Jim Fraser was renamed after Frank Fenner for the 2016 general election This was due to the AEC s plans to name a seat in Victoria in honour of deceased Prime Minister Malcolm Fraser 24 25 References edit Henderson Donald A 2011 Frank Fenner 1914 2010 A guiding light of the campaign to eradicate smallpox Nature 469 7328 35 doi 10 1038 469035a PMID 21209651 Frank F Fenner Donald A Henderson Isao Arita Zdenek Jezek Ivan D Ladnyi Smallpox and its Eradication World Health Organization Geneva 1988 Boyden S Blanden R Mims C 2013 Frank John Fenner FAA 21 December 1914 22 November 2010 Biographical Memoirs of Fellows of the Royal Society 59 125 144 doi 10 1098 rsbm 2013 0009 hdl 1885 65529 S2CID 71415413 Australian Academy of Science Fenner medal Archived from the original on 13 April 2014 Retrieved 13 April 2014 UWA scientist wins Academy Award a b c d Grimes William 25 November 2010 Frank Fenner Dies at 95 Tracked End of Smallpox The New York Times Nepabunna 1937 39 SA Memory State Library of South Australia 28 October 2009 Retrieved 13 November 2020 a b It s an Honour MBE a b Citation record of MBE 1 Fenner School of Environment and Society website Jones Cheryl 15 June 2010 Fenner sees no hope for humans The Australian Edwards Lin 23 June 2010 Humans will be extinct in 100 years says eminent scientist Phys org Retrieved 2 July 2020 Scientist Fenner dies aged 95 Australian Broadcasting Corporation 22 November 2010 Encyclopaedia of Australian Science Chapter 3 Nature Nurture and Chance the lives of Frank and Charles Fenner Chapter 5 Nature Nurture and Chance the lives of Frank and Charles Fenner Suicide Finding in Death of Girl 15 in Canberra Sydney Morning Herald 20 June 1958 p3 Chapter 5 Nature Nurture and Chance the lives of Frank and Charles Fenner Chapter 11 Nature Nurture and Chance the lives of Frank and Charles Fenner It s an Honour CMG Macfarlane Burnet Medal and Lecture Australian Academy of Science Retrieved 22 February 2017 It s an Honour AC World Cultural Council Winners Science Frank Fenner Archived from the original on 29 July 2013 Retrieved 14 August 2013 Jon Stanhope appalled by ACT federal seat renamed from Fraser to Fenner 24 November 2015 Voters call out AEC on Fraser electorate renaming 19 October 2015 External links editOnline Guide to Records at the South Australian Museum Archives Australian Academy of Science Interview with Professor Frank Fenner EmerProfessor Frank Fenner s Webpage at JCMSR Australian War Memorial Honours and Awards Database permanent dead link Stephen Boyden Robert Blanden Cedric Mims Frank John Fenner 1914 2010 PDF Biographical memoirs Australian Academy of Science Originally published in Historical Records of Australian Science vol 24 no 1 pp 109 133 2013 Retrieved from https en wikipedia org w index php title Frank Fenner amp oldid 1151106283, wikipedia, wiki, book, books, library,

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